Feasibility Assessment in Animal Models for Peritoneum Use as Interposition Vessel Graft Substitutes during Living Donor Liver Transplantation
نویسندگان
چکیده
Purpose: Most of the grafts used as interposition conduits for middle hepatic vein (MHV) in living donor liver transplantation (LDLT) have been allografts and autografts. Recently, peritoneum has vessel substitutes during surgery. Thus, we performed animal lab tests to assess feasibility graft MHV. Methods: The inferior vena cava was replaced three dogs pigs with autologous peritoneal graft. After 28 days, patency rate, outer inner diameter, intimal thickness, histology, immunohistochemistry were evaluated according grafts. Results: made all animals at postoperative week 4. diameter anastomotic site four weeks 8.41±0.37 7.41±0.86 mm before surgery after weeks, respectively. 7.90±0.23 6.33±0.68 In histologic findings, intima thickest animals. proliferation smooth muscle cells most severe anti-alpha-actin antibody test anastomosis site. On side peritoneum, endothelial cell migration found over whole segments. Conclusion: Our data implicate that use are feasible MHV reconstruction LDLT.
منابع مشابه
Feasibility Assessment of Interposition Vessel Graft Substitutes in Dog Models for Later Clinical Application to Middle Hepatic Vein Reconstruction during Living Donor Liver Transplantation
Feasibility Assessment of Interposition Vessel Graft Substitutes in Dog Models for Later Clinical Application to Middle Hepatic Vein Reconstruction during Living Donor Liver Transplantation Dong Hwan Jung, M.D., Sung Gyu Lee, M.D., Shin Hwang, M.D., He Nam Hong, Ph.D. Division of Liver Transplantation and Hepatobiliary Surgery, Departments of Surgery and Anatomy and Cell Biology, Asan Medical C...
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ژورنال
عنوان ژورنال: Hpb
سال: 2021
ISSN: ['1365-182X', '1477-2574']
DOI: https://doi.org/10.1016/j.hpb.2020.11.1080